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Amantadin may caus mydiasis and should thnot b givn tpatints with untatd closd-angl glaucoma.
Tll you doctight away i you hav any sious sid cts, including: puplish-d blotchy spots on th skin (spcially on th lgs), swlling th ankls/t, diiculty uinating, vision changs, unusual stong ugs (such as incasd gambling, incasd sxual ugs, uncontolld spnding), mntal/mood changs (such as anxity, dpssion, hallucinations, suicidal thoughts/attmpts), muscl spasms.
A vy sious allgic action tthis dug is a. Howv, gt mdical hlp ight away i you notic any symptoms a sious allgic action, including: ash, itching/swlling (spcially th ac/tongu/thoat), sv dizzinss, toubl bathing.
Th mchanism its antipakinsonic ct is not ully undstood, but it appas tb lasing dopamin om th nv ndings th bain clls, togth with stimulation nopinphin spons. It alshas NMDA cptantagonistic cts. Th antivial mchanism sms tb unlatd. Th dug ints with a vial potin, M2 (an ion channl), which is ndd th vial paticl tbcom « uncoatd » onc it is takn insid th cll by ndocytosis.
Disclaim: Ou goal is tpovid you with th most lvant and cunt inomation. Howv, bcaus dugs intact dintly in ach pson, w cannot guaant that this inomation includs all possibl intactions. This inomation is not a substitut mdical advic. Always spak with you halthca povid about possibl intactions with all psciption dugs, vitamins, hbs and supplmnts, and ov-th-count dugs that you a taking.
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while postexposure prophylaxis with amantadine or rimantadine provided protection in families when the index case did not receive antiviral therapy, the drugs did not provide protection from influenza a infection in household contacts when amantadine or rimantadine was used to treat the index case, presumably because of spread of resistant virus within the household.