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Rizatriptan should only be used where a clear diagnosis of migraine has been establishedRizatriptan should not be administered to patients with basilar or haemiplegic migraineAs with other 5-HT 1B1D agonistssensations of tightnesspainpressure and heaviness have been reported after treatment with rizatriptan in the precordiumthroatneck and jawThese events have not been associated with arrhythmias or definite ischaemic electrocardiogramECGchanges in clinical trialsone patient experienced chest pain with possible ischaemic ECG changesBecause drugs in this class may cause coronary artery vasospasmpatients who experience signs or symptoms suggestive of angina following dosing should be evaluated for the presence of coronary artery diseaseCADor a predisposition to Prinzmetal’s variant angina before receiving additional doses of medicationand should be monitored by ECG if dosing is resumed and similar symptoms recurSimilarlypatients who experience other symptoms or signs suggestive of decreased arterial flowsuch as ischaemic bowel syndrome or Raynaud’s syndrome following the use of any 5-HT 1 agonist are candidates for further evaluation.

There are no adequate and well-controlled studies in pregnant womenthereforerizatriptan should be used during pregnancy only if the potential benefit justifies the potential risk to the foetus.

Triptanssuch as rizatriptanMaxaltor almotriptanAxertAntinausea medicinessuch as chlorpromazineThorazinepromethazinePhenerganor prochlorperazineCompazineNon-steroidal anti-inflammatory drugsNSAIDssuch as acetaminophennaproxen sodiumaspirin or ibuprofen.

Make changes in your diet such as avoid such foodsincluding caffeine and alcohol which are believed to trigger headachesYou can also try muscle relaxation exercisesyoga or meditation to ease the migraine attack.

RacePharmacokinetic data revealed no significant differences between African-American and Caucasian subjects.

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