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Because its mechanism of action is differentthe effect of Precose to enhance glycemic control is additive to that of sulfonylureasinsulin or metformin when used in combinationIn additionPrecose diminishes the insulinotropic and weight-increasing effects of sulfonylureas.
Get emergency medical help if you have any of these signs of an allergic reactionhivesdifficulty breathingswelling of your facelipstongueor throat.
Ask your doctor how to adjust your acarbose dose if neededDo not change your medication dose or schedule without your doctor’s advice.
Clinical Experience in Type 2 Diabetes Mellitus Patients on Monotherapyor in Combination with SulfonylureasMetformin or InsulinPrecose was studied as monotherapy and as combination therapy to sulfonylureametforminor insulin treatmentThe treatment effects on HbA1c levels and one-hour postprandial glucose levels are summarized for four placebo-controlleddouble-blindrandomized studies conducted in the United States in Tables 2 and 3respectivelyThe placebo-subtracted treatment differenceswhich are summarized belowwere statistically significant for both variables in all of these studies.
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