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Some young people have thoughts about suicide when first taking an antidepressantYour doctor should check your progress at regular visitsYour family or other caregivers should also be alert to changes in your mood or symptoms.

Compounds of structure2are prepared by reaction of an arecoline analogue of structure(4with an organometallic compound containing an X-substituted phenyl groupsuch as a compound of structure3STR1Suitably the compound of structure3is a Grignard reagentwhere M is magnesium and Y is a halogen atomor M may be a Group II metal and Y is a halogen atom or a second X-substituted phenyl groupWhen structure3is a Grignard reagentthe reaction is carried out either in a suitable non-ether solventtypically a hydrocarbon or a non-reactive chlorinated hydrocarbonor in a mixture of such a solvent with diethyl etherCompounds of structure2are important intermediates in the preparation of inter alia paroxetine.

Shake the oral suspensionliquidwell just before you measure a doseMeasure liquid medicine with the dosing syringe providedor with a special dose-measuring spoon or medicine cupIf you do not have a dose-measuring deviceask your pharmacist for one.

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