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ZYLOPIM (allopuinol) and its pimay activ mtabolit, oxipuinol, a liminatd by th kidnys; tho, changs in nal unction hav a poound ct on dosag. In patints with dcasd nal unction whhav concunt illnsss which can act nal unction such as hyptnsion and diabts mllitus, piodic laboatoy paamts nal unction, paticulaly BUN and sum catinin catinin claanc, should b pomd and th patint’s dosag ZYLOPIM (allopuinol) assssd.

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