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For people with kidney diseaseThe initial dosage of Droxia is 7.5 mg per kilogram of body weighttaken once per day.

For women who are breastfeedingHydroxyurea may pass into breast milk and cause side effects in a child who is breastfedYou should stop breastfeeding when you are taking hydroxyureaTalk to your doctor if you breastfeed your child.

This medication may be covered under your prescription drug planPatient assistance may be available to qualifying individuals depending upon prescription drug coverageCo-pay cardswhich reduce the patient co-pay responsibility for eligible commerciallynon-government sponsoredinsured patientsmay also be availableYour care team can help you find these resourcesif they are available.

Three mechanisms of action have been postulated for the increased effectiveness of concomitant use of hydroxyurea therapy with irradiation on squamous cellepidermoidcarcinomas of the head and neckIn vitro studies utilizing Chinese hamster cells suggest that hydroxyurea1is lethal to normally radioresistant S-stage cellsand2holds other cells of the cell cycle in the G1 or pre-DNA synthesis stage where they are most susceptible to the effects of irradiationThe third mechanism of action has been theorized on the basis of in vitro studies of HeLa cellsIt appears that hydroxyureaby inhibition of DNA synthesishinders the normal repair process of cells damaged but not killed by irradiationthereby decreasing their survival rateRNA and protein syntheses have shown no alteration.

DisclaimerOur goal is to provide you with the most relevant and current informationHoweverbecause drugs affect each person differentlywe cannot guarantee that this list includes all possible dosagesThis information is not a substitute for medical adviceAlways speak with your doctor or pharmacist about dosages that are right for you.

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